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With each passing day, the skin ages faster

As we age, the production of new skin cells slows down, accelerating the skin's aging process. There is only one scientifically proven way to counteract this. Every day counts — the sooner we start treatment, the better the results.

Trust in the world’s most powerful anti-aging ingredient

Backed by more scientific studies than any other active ingredient — proven to deliver visible results.

All source information can be

found at the bottom of the page.

Have you tried it before but had trouble tolerating it?

Regular retinol can be too harsh for sensitive skin, causing irritation and forcing many to discontinue use.

This is why we created Retixol

With RetiXol, application is easy and suitable for everyone. To achieve this, we have enhanced pure retinol with plant-based compounds derived from the green leaves of the tobacco plant. These natural actives mimic the effects of retinol, making the treatment both gentler and more effective at the same time."


Retinol + Plant Compounds = RetiXol

The result is truly unique

Over 1 million customers worldwide can't be wrong

retixol test

Over a million customers already trust us. Take advantage of our 30-day money-back guarantee and see the results for yourself. If you don’t notice any improvement, you’ll get your money back — no questions asked.

Available online and in pharmacies all across Europe

You can also find RETIXOL at your local pharmacy in Europe. If your pharmacist does not have the cream in stock, it can usually be delivered to the pharmacy within a few hours. Pharmacy central number: -18444329.

We only use 100% pure and laboratory-tested ingredients

Our production is certified according to the ISO 13485 standard. This certification defines the requirements for the development and manufacturing of medical devices, ensuring the highest quality standards for companies like ours."


In addition, our production is local. This allows us to support regional jobs while maintaining 100% control over the entire manufacturing process.

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FAQ

Who is RetiXol suitable for?

RetiXol is designed for women of all ages and skin types. The sooner you begin, the better your skin will look over time. Every day makes a difference.

How is RetiXol made?

Our active ingredient is created through a proprietary process that gently extracts plant compounds from tobacco leaves and combines them with retinol. This unique method, known as Phyto-Lysis, was developed by Evertz Pharma GmbH.

When should I use RetiXol?

For best results, apply at night. This gives the active ingredient time to deeply absorb into the skin and work effectively without being degraded by sunlight or other environmental factors.

What should be considered when dosing RetiXol?

The dosage has been carefully selected to allow the active ingredient to deliver its optimal effect without causing skin irritation. There are no special precautions — the cream can be applied in any amount as needed. It is also suitable for individuals who are sensitive to regular retinol or have never used retinol before.

Does RetiXol really work that well?

RetiXol has proven effective for over a million users worldwide. The unique combination of retinol and gently extracted plant compounds provides intensive support for the skin’s natural regeneration processes. No other ingredient is backed by as many scientific studies confirming its effectiveness. Users consistently report visibly smoother and fresher-looking skin after just a short period of use.

How much retinol is contained in it?

For confidentiality reasons, the exact retinol concentration is not disclosed, as it is regarded as proprietary information by the manufacturer.

Do I need any other skincare products?

You don’t need any other anti-aging products. If your skin feels dry, a regular moisturizer in the morning is perfectly sufficient.

Clinical studies and

scientific research

Scientific Studies on Vitamin A

Here you’ll find several scientific studies demonstrating the effectiveness of Vitamin A (including retinol and related retinoids) in addressing skin aging and skin renewal. These studies primarily focus on improvements in wrinkles, skin texture, and moisture levels:

Kafi R, Kwak HS, Schumacher WE, Cho S, Hanft VN, Kang S, Fisher GJ, Voorhees JJ, Varani J. (2007). Improvement of Naturally Aged Skin with Vitamin A (Retinol). Archives of Dermatology, 143(5), 606-12.

Result: Topical retinol led to a significant improvement in fine lines and increased collagen production in naturally aged skin.

Varani J, Fisher GJ, Kang S, Voorhees JJ. (2016). Molecular mechanisms of intrinsic skin aging and retinoid therapy. Dermatologic Therapy, 29(5), 364–375.

Result: Shows the molecular mechanisms by which retinoids (including retinol) promote collagen synthesis while inhibiting collagen breakdown.

Kang S, Leyden JJ, Lowe NJ, Matts PJ, Kollias N, Larnier C, et al. (2001). Photodamage and Topical Retinoic Acid Therapy. Journal of the European Academy of Dermatology and Venereology, 15(Suppl 3), 28-33.

Result: Retinoic acid (the active form of Vitamin A) improves signs of photoaging such as wrinkles and hyperpigmentation.

Kim J, Kim S, Shin HS, Kim J, Jung E, et al. (2013). Efficacy of Retinyl Retinoate in the Improvement of Photoaged Skin. Dermatologic Therapy, 26(4), 267-271.

Result: Retinyl retinoate (a gentler form of retinol) causes less skin irritation while still effectively improving fine lines and skin texture.

Griffiths CEM, Kang S, Ellis CN, et al. (1995). Two concentrations of topical retinoic acid cause similar improvement of photodamage. Journal of the American Academy of Dermatology, 33(3), 384-390.

Result: Even at different concentrations, retinoic acid showed comparable improvements in wrinkles and skin texture.

retixol evertz pharma

Evertz Pharma GmbH

Frankfurt am Main | Deutschland


MADE IN GERMANY

retixol

Detailed Sources/References


Byrdie – “Anti-Aging Ingredients: The Biology Behind Them”

Published on: February 22, 2024

This article explains the scientific background and biological effects of key anti-aging ingredients. For complete details, visit:

https://www.byrdie.com/anti-aging-ingredients-biology


Health – “Best Retinol Cream”

Published on: February 14, 2025

In this piece, Health reviews top retinol creams and discusses the benefits of retinol in skincare regimens. Read more at:

https://www.health.com/beauty/best-retinol-cream


Prevention – “Retinol Benefits”

Published on: December 13, 2019

This Prevention article outlines the benefits of retinol for skin health and anti-aging, providing insights into its practical applications. More information is available at:

https://www.prevention.com/beauty/skin-care/a30027574/retinol-benefits/


Vogue – “How to Layer Your Skincare Products”

Published on: September 29, 2024

Vogue’s guide on layering skincare products includes expert advice on combining retinol with other ingredients effectively. Discover the full article at:

https://www.vogue.com/article/how-to-layer-your-skincare-products


Vogue UK – “What Is Retinol”

Published on: February 10, 2025

This article from Vogue UK provides an in-depth explanation of retinol, its uses, and benefits within modern skincare routines. Read the article at:

https://www.vogue.co.uk/article/what-is-retinol






Customer satisfaction measured via a Typeform survey, December 2022, n=200. Results may vary from person to person. Names have been changed. Image is a representation.


Evertz Pharma

As one of the leading innovators in German pharmaceutical research, we are dedicated to creating products based on natural ingredients. Our mission: to address the root causes of health concerns, not just the symptoms. Discover more at  Evertz-Pharma.com